Transethnic meta-analysis suggests genetic variation in the HEME pathway influences potassium response in patients treated with hydrochlorothiazide. [electronic resource]
- The pharmacogenomics journal Apr 2015
- 153-7 p. digital
Publication Type: Journal Article; Meta-Analysis; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1473-1150
10.1038/tpj.2014.46 doi
Black or African American--genetics Antihypertensive Agents--therapeutic use Bayes Theorem Carrier Proteins--genetics Cation Transport Proteins--genetics Chromosomes, Human, Pair 12--genetics Chromosomes, Human, Pair 8--genetics Female Genome-Wide Association Study--methods Heme--genetics Heme-Binding Proteins Hemeproteins--genetics Humans Hydrochlorothiazide--metabolism Hypertension--drug therapy Hypokalemia--drug therapy Male Middle Aged Mitochondrial Proteins--genetics Polymorphism, Single Nucleotide--genetics Potassium--metabolism White People--genetics