TY  - GEN
AU  - Worek,Franz
AU  - Seeger,Thomas
AU  - Reiter,Georg
AU  - Goldsmith,Moshe
AU  - Ashani,Yacov
AU  - Leader,Haim
AU  - Sussman,Joel L
AU  - Aggarwal,Nidhi
AU  - Thiermann,Horst
AU  - Tawfik,Dan S
TI  - Post-exposure treatment of VX poisoned guinea pigs with the engineered phosphotriesterase mutant C23: a proof-of-concept study
SN  - 1879-3169
PY  - 2015///0202
KW  - Acetylcholinesterase
KW  - blood
KW  - Animals
KW  - Antidotes
KW  - administration & dosage
KW  - Brain
KW  - drug effects
KW  - Catalysis
KW  - Chemical Warfare Agents
KW  - metabolism
KW  - Cholinesterase Inhibitors
KW  - Drug Administration Schedule
KW  - Erythrocytes
KW  - Guinea Pigs
KW  - Hydrolysis
KW  - Male
KW  - Mutation
KW  - Neurotoxicity Syndromes
KW  - Organothiophosphorus Compounds
KW  - Phosphoric Triester Hydrolases
KW  - Protein Engineering
KW  - Recombinant Proteins
KW  - Time Factors
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1016/j.toxlet.2014.09.003
ER  -