TY - GEN AU - Lyon,Robert P AU - Setter,Jocelyn R AU - Bovee,Tim D AU - Doronina,Svetlana O AU - Hunter,Joshua H AU - Anderson,Martha E AU - Balasubramanian,Cindy L AU - Duniho,Steven M AU - Leiske,Chris I AU - Li,Fu AU - Senter,Peter D TI - Self-hydrolyzing maleimides improve the stability and pharmacological properties of antibody-drug conjugates SN - 1546-1696 PY - 2015///0615 KW - Animals KW - Antibodies KW - chemistry KW - Antineoplastic Agents KW - Cell Proliferation KW - drug effects KW - Excipients KW - Female KW - Humans KW - Hydrogen-Ion Concentration KW - Hydrolysis KW - Immunoconjugates KW - Maleimides KW - Mice KW - Mice, SCID KW - Plasma KW - Xenograft Model Antitumor Assays N1 - Publication Type: Journal Article UR - https://doi.org/10.1038/nbt.2968 ER -