Chen, Qing

Grape seed proanthocyanidins (GSPs) inhibit the growth of cervical cancer by inducing apoptosis mediated by the mitochondrial pathway. [electronic resource] - PloS one 2014 - e107045 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1932-6203

10.1371/journal.pone.0107045 doi


Animals
Antineoplastic Agents, Phytogenic--pharmacology
Apoptosis--drug effects
Caspase 3--genetics
Cell Line, Tumor
Female
Gene Expression Regulation, Neoplastic
Grape Seed Extract--pharmacology
Humans
Membrane Potential, Mitochondrial--drug effects
Mice
Mice, Nude
Mitochondria--drug effects
Proanthocyanidins--pharmacology
Proto-Oncogene Proteins c-bcl-2--antagonists & inhibitors
Signal Transduction--drug effects
Transplantation, Heterotopic
Tumor Burden--drug effects
Uterine Cervical Neoplasms--drug therapy
Xenograft Model Antitumor Assays
bcl-2 Homologous Antagonist-Killer Protein--agonists