TY  - GEN
AU  - Hasui,Tomoaki
AU  - Ohyabu,Norio
AU  - Ohra,Taiichi
AU  - Fuji,Koji
AU  - Sugimoto,Takahiro
AU  - Fujimoto,Jun
AU  - Asano,Kouhei
AU  - Oosawa,Masato
AU  - Shiotani,Sachiko
AU  - Nishigaki,Nobuhiro
AU  - Kusumoto,Keiji
AU  - Matsui,Hideki
AU  - Mizukami,Atsushi
AU  - Habuka,Noriyuki
AU  - Sogabe,Satoshi
AU  - Endo,Satoshi
AU  - Ono,Midori
AU  - Siedem,Christopher S
AU  - Tang,Tony P
AU  - Gauthier,Cassandra
AU  - De Meese,Lisa A
AU  - Boyd,Steven A
AU  - Fukumoto,Shoji
TI  - Discovery of 6-[5-(4-fluorophenyl)-3-methyl-pyrazol-4-yl]-benzoxazin-3-one derivatives as novel selective nonsteroidal mineralocorticoid receptor antagonists
SN  - 1464-3391
PY  - 2015///0406
KW  - Androgen Antagonists
KW  - administration & dosage
KW  - Animals
KW  - Antihypertensive Agents
KW  - COS Cells
KW  - Chlorocebus aethiops
KW  - Crystallography, X-Ray
KW  - Desoxycorticosterone Acetate
KW  - Dose-Response Relationship, Drug
KW  - Drug Discovery
KW  - Humans
KW  - Hypertension
KW  - chemically induced
KW  - Male
KW  - Mineralocorticoid Receptor Antagonists
KW  - Models, Molecular
KW  - Molecular Structure
KW  - Oxazines
KW  - Pyrazoles
KW  - Rats
KW  - Rats, Wistar
KW  - Receptors, Mineralocorticoid
KW  - agonists
KW  - Structure-Activity Relationship
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1016/j.bmc.2014.07.038
ER  -