TY  - GEN
AU  - Conn,P Jeffrey
AU  - Lindsley,Craig W
AU  - Meiler,Jens
AU  - Niswender,Colleen M
TI  - Opportunities and challenges in the discovery of allosteric modulators of GPCRs for treating CNS disorders
SN  - 1474-1784
PY  - 2014///1031
KW  - Allosteric Regulation
KW  - drug effects
KW  - Animals
KW  - Central Nervous System Agents
KW  - chemistry
KW  - Central Nervous System Diseases
KW  - drug therapy
KW  - Drug Discovery
KW  - methods
KW  - Humans
KW  - Receptors, G-Protein-Coupled
KW  - metabolism
KW  - Treatment Outcome
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Review
UR  - https://doi.org/10.1038/nrd4308
ER  -