Opportunities and challenges in the discovery of allosteric modulators of GPCRs for treating CNS disorders. [electronic resource]
- Nature reviews. Drug discovery Sep 2014
- 692-708 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Review
1474-1784
10.1038/nrd4308 doi
Allosteric Regulation--drug effects Animals Central Nervous System Agents--chemistry Central Nervous System Diseases--drug therapy Drug Discovery--methods Humans Receptors, G-Protein-Coupled--metabolism Treatment Outcome