TY  - GEN
AU  - Liu,Zhibo
AU  - Chen,Xinxin
AU  - Wang,Ying
AU  - Peng,Haiyong
AU  - Wang,Yanan
AU  - Jing,Yanling
AU  - Zhang,Hongbing
TI  - PDK4 protein promotes tumorigenesis through activation of cAMP-response element-binding protein (CREB)-Ras homolog enriched in brain (RHEB)-mTORC1 signaling cascade
SN  - 1083-351X
PY  - 2015///0212
KW  - AMP-Activated Protein Kinases
KW  - metabolism
KW  - Aerobiosis
KW  - drug effects
KW  - Animals
KW  - Carcinogenesis
KW  - Cell Line, Tumor
KW  - Cell Proliferation
KW  - Cyclic AMP Response Element-Binding Protein
KW  - Dichloroacetic Acid
KW  - pharmacology
KW  - Glycolysis
KW  - HEK293 Cells
KW  - Humans
KW  - Hypoxia-Inducible Factor 1, alpha Subunit
KW  - Isoenzymes
KW  - Mechanistic Target of Rapamycin Complex 1
KW  - Mice
KW  - Mice, Nude
KW  - Monomeric GTP-Binding Proteins
KW  - Multiprotein Complexes
KW  - antagonists & inhibitors
KW  - Neuropeptides
KW  - PTEN Phosphohydrolase
KW  - Protein Kinases
KW  - Proto-Oncogene Proteins c-akt
KW  - Pyruvate Kinase
KW  - Ras Homolog Enriched in Brain Protein
KW  - Signal Transduction
KW  - TOR Serine-Threonine Kinases
KW  - Transcription, Genetic
KW  - Tuberous Sclerosis Complex 2 Protein
KW  - Tumor Suppressor Proteins
KW  - Up-Regulation
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1074/jbc.M114.584821
ER  -