Peng, Joanna Z <br/><br/>
A semi-mechanistic model for the effects of a novel glucagon receptor antagonist on glucagon and the interaction between glucose, glucagon, and insulin applied to adaptive phase II design.  [electronic resource] 

 -  The AAPS journal  Nov 2014 
 - 1259-70 p.  digital 
<br/><br/> Publication Type: Clinical Trial, Phase II; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1550-7416 
<br/><br/><label>Standard No.: </label>10.1208/s12248-014-9648-x  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Adult<br/>Blood Glucose--analysis<br/>Cross-Over Studies<br/>Diabetes Mellitus, Type 2--blood<br/>Double-Blind Method<br/>Drug Administration Schedule<br/>Drug Interactions<br/>Female<br/>Glucagon--administration & dosage<br/>Glucose--metabolism<br/>Humans<br/>Hypoglycemic Agents--administration & dosage<br/>Insulin--administration & dosage<br/>Male<br/>Middle Aged<br/>Models, Biological<br/>Receptors, Glucagon--antagonists & inhibitors