TY - GEN AU - Ma,Quan AU - Ying,Ming AU - Sui,Xiaojing AU - Zhang,Huimin AU - Huang,Haiyan AU - Yang,Linqing AU - Huang,Xinfeng AU - Zhuang,Zhixiong AU - Liu,Jianjun AU - Yang,Xifei TI - Chronic copper exposure causes spatial memory impairment, selective loss of hippocampal synaptic proteins, and activation of PKR/eIF2α pathway in mice SN - 1875-8908 PY - 2015///0818 KW - 8-Hydroxy-2'-Deoxyguanosine KW - Activating Transcription Factor 4 KW - metabolism KW - Animals KW - Apoptosis KW - drug effects KW - Chronic Disease KW - Copper Sulfate KW - toxicity KW - Cyclic AMP Response Element-Binding Protein KW - DNA-Binding Proteins KW - Deoxyguanosine KW - analogs & derivatives KW - Disks Large Homolog 4 Protein KW - Guanylate Kinases KW - Hippocampus KW - Male KW - Membrane Proteins KW - Memory Disorders KW - chemically induced KW - Mice, Inbred C57BL KW - Neurons KW - Oxidative Stress KW - Random Allocation KW - Signal Transduction KW - Spatial Memory KW - Synapsins KW - Transcription Factor CHOP KW - Transcription Factors KW - Tyrosine KW - eIF-2 Kinase N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.3233/JAD-140216 ER -