Ma, Quan <br/><br/>
Chronic copper exposure causes spatial memory impairment, selective loss of hippocampal synaptic proteins, and activation of PKR/eIF2α pathway in mice.  [electronic resource] 

 -  Journal of Alzheimer's disease : JAD  2015 
 - 1413-27 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1875-8908 
<br/><br/><label>Standard No.: </label>10.3233/JAD-140216  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>8-Hydroxy-2'-Deoxyguanosine<br/>Activating Transcription Factor 4--metabolism<br/>Animals<br/>Apoptosis--drug effects<br/>Chronic Disease<br/>Copper Sulfate--toxicity<br/>Cyclic AMP Response Element-Binding Protein--metabolism<br/>DNA-Binding Proteins--metabolism<br/>Deoxyguanosine--analogs & derivatives<br/>Disks Large Homolog 4 Protein<br/>Guanylate Kinases--metabolism<br/>Hippocampus--drug effects<br/>Male<br/>Membrane Proteins--metabolism<br/>Memory Disorders--chemically induced<br/>Mice, Inbred C57BL<br/>Neurons--drug effects<br/>Oxidative Stress--drug effects<br/>Random Allocation<br/>Signal Transduction--drug effects<br/>Spatial Memory--drug effects<br/>Synapsins--metabolism<br/>Transcription Factor CHOP--metabolism<br/>Transcription Factors--metabolism<br/>Tyrosine--analogs & derivatives<br/>eIF-2 Kinase--metabolism