Chen, Huadong <br/><br/>
Ginger compound [6]-shogaol and its cysteine-conjugated metabolite (M2) activate Nrf2 in colon epithelial cells in vitro and in vivo.  [electronic resource] 

 -  Chemical research in toxicology  Sep 2014 
 - 1575-85 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural 
<br/><br/><label>ISSN: </label>1520-5010 
<br/><br/><label>Standard No.: </label>10.1021/tx500211x  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Alkylation<br/>Animals<br/>Catechols--chemistry<br/>Cysteine--analysis<br/>Epithelial Cells--cytology<br/>Zingiber officinale--chemistry<br/>Glutamate-Cysteine Ligase--metabolism<br/>Glutathione--metabolism<br/>HCT116 Cells<br/>Heme Oxygenase-1--metabolism<br/>Humans<br/>Intracellular Signaling Peptides and Proteins--chemistry<br/>Kelch-Like ECH-Associated Protein 1<br/>Membrane Proteins--metabolism<br/>Mice<br/>Mice, Knockout<br/>NF-E2-Related Factor 2--deficiency<br/>Phosphorylation--drug effects<br/>Protein Kinase Inhibitors--pharmacology<br/>Reactive Oxygen Species--metabolism<br/>Up-Regulation--drug effects