Wang, Shaomeng <br/><br/>
SAR405838: an optimized inhibitor of MDM2-p53 interaction that induces complete and durable tumor regression.  [electronic resource] 

 -  Cancer research  Oct 2014 
 - 5855-65 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S. 
<br/><br/><label>ISSN: </label>1538-7445 
<br/><br/><label>Standard No.: </label>10.1158/0008-5472.CAN-14-0799  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Antineoplastic Agents--pharmacology<br/>Apoptosis--drug effects<br/>Apoptosis Regulatory Proteins--metabolism<br/>Cell Cycle Checkpoints<br/>Cell Proliferation--drug effects<br/>Dogs<br/>Drug Stability<br/>HCT116 Cells<br/>Humans<br/>Indoles--pharmacology<br/>Mice<br/>Protein Binding<br/>Proto-Oncogene Proteins--metabolism<br/>Proto-Oncogene Proteins c-mdm2--metabolism<br/>Rats<br/>Remission Induction<br/>Spiro Compounds--pharmacology<br/>Tumor Suppressor Protein p53--metabolism<br/>Xenograft Model Antitumor Assays