TY - GEN AU - Kidwell,Mary Anne AU - Chan,Jessica M AU - Doudna,Jennifer A TI - Evolutionarily conserved roles of the dicer helicase domain in regulating RNA interference processing SN - 1083-351X PY - 2015///0206 KW - Adenosine Triphosphate KW - chemistry KW - Amino Acid Sequence KW - Animals KW - Baculoviridae KW - genetics KW - Biological Evolution KW - Conserved Sequence KW - DNA Helicases KW - Fungal Proteins KW - Gene Expression Regulation, Fungal KW - Humans KW - Hydrolysis KW - Isoenzymes KW - MicroRNAs KW - biosynthesis KW - Molecular Sequence Data KW - Protein Structure, Secondary KW - Protein Structure, Tertiary KW - RNA Interference KW - RNA, Double-Stranded KW - Recombinant Proteins KW - Ribonuclease III KW - Sf9 Cells KW - Signal Transduction KW - Spodoptera KW - Sporothrix KW - Substrate Specificity N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1074/jbc.M114.589051 ER -