TY - GEN AU - Walsh,Craig M AU - Fruman,David A TI - Too much of a good thing: immunodeficiency due to hyperactive PI3K signaling SN - 1558-8238 PY - 2015///0120 KW - Class Ia Phosphatidylinositol 3-Kinase KW - Female KW - Humans KW - Immunologic Deficiency Syndromes KW - genetics KW - Male KW - Mutation KW - Phosphatidylinositol 3-Kinases N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Comment UR - https://doi.org/10.1172/JCI77198 ER -