TY - GEN AU - Perez-Carbonell,Lucia AU - Balaguer,Francesc AU - Toiyama,Yuji AU - Egoavil,Cecilia AU - Rojas,Estefania AU - Guarinos,Carla AU - Andreu,Montserrat AU - Llor,Xavier AU - Castells,Antoni AU - Jover,Rodrigo AU - Boland,C Richard AU - Goel,Ajay TI - IGFBP3 methylation is a novel diagnostic and predictive biomarker in colorectal cancer SN - 1932-6203 PY - 2015///1109 KW - Aged KW - Aged, 80 and over KW - Antineoplastic Combined Chemotherapy Protocols KW - therapeutic use KW - Biomarkers, Tumor KW - genetics KW - Colorectal Neoplasms KW - diagnosis KW - CpG Islands KW - DNA Methylation KW - Female KW - Humans KW - Insulin-Like Growth Factor Binding Protein 3 KW - Intestinal Mucosa KW - metabolism KW - Male KW - Microsatellite Instability KW - Microsatellite Repeats KW - Middle Aged KW - Mutation KW - Neoplasm Staging KW - Prognosis KW - Promoter Regions, Genetic KW - Proto-Oncogene Proteins B-raf KW - Treatment Outcome N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1371/journal.pone.0104285 ER -