Deficiency of the two-pore-domain potassium channel TREK-1 promotes hyperoxia-induced lung injury. [electronic resource]
- Critical care medicine Nov 2014
- e692-701 p. digital
Publication Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1530-0293
10.1097/CCM.0000000000000603 doi
Acute Lung Injury--etiology Animals Blotting, Western Bronchoalveolar Lavage Fluid--chemistry Cytokines--genetics Disease Models, Animal Enzyme-Linked Immunosorbent Assay Hyperoxia--complications Macrophages, Alveolar--metabolism Male Mice Mice, Inbred C57BL Microscopy, Confocal--methods Potassium Channels, Tandem Pore Domain--deficiency Random Allocation Real-Time Polymerase Chain Reaction Reference Values Respiration, Artificial Risk Assessment Severity of Illness Index