Wang, Zhiren <br/><br/>
Design, synthesis, and evaluation of multitarget-directed selenium-containing clioquinol derivatives for the treatment of Alzheimer's disease.  [electronic resource] 

 -  ACS chemical neuroscience  Oct 2014 
 - 952-62 p.  digital 
<br/><br/> Publication Type: Evaluation Study; Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1948-7193 
<br/><br/><label>Standard No.: </label>10.1021/cn500119g  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Alzheimer Disease--drug therapy<br/>Amyloid beta-Peptides--metabolism<br/>Animals<br/>Antioxidants--chemical synthesis<br/>Blood-Brain Barrier--metabolism<br/>Capillary Permeability<br/>Cell Line, Tumor<br/>Cell Survival--drug effects<br/>Clioquinol--analogs & derivatives<br/>Copper--toxicity<br/>Drug Design<br/>Drug Evaluation, Preclinical<br/>Humans<br/>Hydrogen Peroxide--metabolism<br/>Membranes, Artificial<br/>Models, Biological<br/>Nootropic Agents--chemical synthesis<br/>Peptide Fragments--metabolism<br/>Protein Multimerization--drug effects<br/>Selenium Compounds--chemical synthesis<br/>Swine