Hegde, Sharath S <br/><br/>
Pharmacologic characterization of GSK-961081 (TD-5959), a first-in-class inhaled bifunctional bronchodilator possessing muscarinic receptor antagonist and β2-adrenoceptor agonist properties.  [electronic resource] 

 -  The Journal of pharmacology and experimental therapeutics  Oct 2014 
 - 190-9 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1521-0103 
<br/><br/><label>Standard No.: </label>10.1124/jpet.114.216861  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Adrenergic beta-2 Receptor Antagonists--adverse effects<br/>Albuterol--analogs & derivatives<br/>Animals<br/>Bronchodilator Agents--adverse effects<br/>CHO Cells<br/>Carbamates--adverse effects<br/>Cricetinae<br/>Cricetulus<br/>Cyclic AMP--metabolism<br/>Drug Evaluation, Preclinical<br/>Guinea Pigs<br/>HEK293 Cells<br/>Humans<br/>Lung--drug effects<br/>Muscarinic Antagonists--adverse effects<br/>Muscle Relaxation<br/>Muscle, Smooth--drug effects<br/>Protein Binding<br/>Quinolones--adverse effects<br/>Receptors, Adrenergic, beta--metabolism<br/>Receptors, Muscarinic--metabolism<br/>Salmeterol Xinafoate<br/>Scopolamine Derivatives--pharmacokinetics<br/>Tiotropium Bromide<br/>Tissue Distribution<br/>Trachea--drug effects