Restricted isotype, distinct variable gene usage, and high rate of gp120 specificity of HIV-1 envelope-specific B cells in colostrum compared with those in blood of HIV-1-infected, lactating African women. [electronic resource]
- Mucosal immunology Mar 2015
- 316-26 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1935-3456
10.1038/mi.2014.69 doi
Black or African American Antibody Formation--immunology B-Lymphocytes--cytology CD4 Lymphocyte Count Clonal Evolution Colostrum--cytology Complementarity Determining Regions--genetics Epitopes, B-Lymphocyte--immunology Female HIV Antibodies--immunology HIV Envelope Protein gp120--immunology HIV Envelope Protein gp41--immunology HIV Infections--blood HIV-1--immunology Humans Immunoglobulin G--blood Immunoglobulin Heavy Chains--genetics Immunoglobulin Variable Region--genetics Immunologic Memory Immunophenotyping Infectious Disease Transmission, Vertical Lactation Mutation Rate Phenotype Somatic Hypermutation, Immunoglobulin Viral Load