TY - GEN AU - Ghannam,Khetam AU - Martinez-Gamboa,Lorena AU - Spengler,Lydia AU - Krause,Sabine AU - Smiljanovic,Biljana AU - Bonin,Marc AU - Bhattarai,Salyan AU - Grützkau,Andreas AU - Burmester,Gerd-R AU - Häupl,Thomas AU - Feist,Eugen TI - Upregulation of immunoproteasome subunits in myositis indicates active inflammation with involvement of antigen presenting cells, CD8 T-cells and IFNΓ SN - 1932-6203 PY - 2015///0411 KW - Adult KW - Aged KW - CD8-Positive T-Lymphocytes KW - enzymology KW - Dendritic Cells KW - Female KW - Gene Expression Regulation, Enzymologic KW - immunology KW - Humans KW - Interferon Regulatory Factor-1 KW - Interferon-gamma KW - biosynthesis KW - Male KW - Middle Aged KW - Muscle Proteins KW - Myositis KW - Proteasome Endopeptidase Complex KW - STAT1 Transcription Factor KW - Up-Regulation N1 - Publication Type: Clinical Trial; Comparative Study; Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1371/journal.pone.0104048 ER -