Dose-dependent differential response of mammalian cells to cytoplasmic stress is mediated through the heme-regulated eIF2α kinase. [electronic resource]
- The international journal of biochemistry & cell biology Sep 2014
- 186-97 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1878-5875
10.1016/j.biocel.2014.07.016 doi
Apoptosis--drug effects Blotting, Western Cell Cycle--drug effects Cell Proliferation--drug effects Cells, Cultured Cytoplasm--drug effects Databases, Protein Dose-Response Relationship, Drug HeLa Cells Humans K562 Cells Organometallic Compounds--pharmacology Phosphatidylinositol 3-Kinases--genetics Phosphorylation Protein Interaction Domains and Motifs Proto-Oncogene Proteins c-akt--genetics RNA, Messenger--genetics RNA, Small Interfering--genetics Real-Time Polymerase Chain Reaction Reverse Transcriptase Polymerase Chain Reaction Stress, Physiological eIF-2 Kinase--antagonists & inhibitors