Kunita-Takanezawa, Mutsumi <br/><br/>
Novel dual endothelin receptor antagonist macitentan reverses severe pulmonary arterial hypertension in rats.  [electronic resource] 

 -  Journal of cardiovascular pharmacology  Nov 2014 
 - 473-80 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1533-4023 
<br/><br/><label>Standard No.: </label>10.1097/FJC.0000000000000141  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Disease Models, Animal<br/>Dose-Response Relationship, Drug<br/>Endothelin A Receptor Antagonists--administration & dosage<br/>Endothelin B Receptor Antagonists--administration & dosage<br/>Hypertension, Pulmonary--drug therapy<br/>Hypertrophy, Right Ventricular--drug therapy<br/>Indoles--pharmacology<br/>Male<br/>Pyrimidines--administration & dosage<br/>Pyrroles--pharmacology<br/>Rats<br/>Rats, Sprague-Dawley<br/>Severity of Illness Index<br/>Sulfonamides--administration & dosage<br/>Time Factors<br/>Vascular Endothelial Growth Factor A--antagonists & inhibitors