Yazama, Hiroaki

Dietary glucosylceramides suppress tumor growth in a mouse xenograft model of head and neck squamous cell carcinoma by the inhibition of angiogenesis through an increase in ceramide. [electronic resource] - International journal of clinical oncology Jun 2015 - 438-46 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1437-7772

10.1007/s10147-014-0734-y doi


Administration, Oral
Angiogenesis Inhibitors--administration & dosage
Animals
Carcinoma, Squamous Cell--diet therapy
Ceramides--biosynthesis
Glucosylceramides--administration & dosage
Head and Neck Neoplasms--diet therapy
Humans
Hypoxia-Inducible Factor 1, alpha Subunit--biosynthesis
Mice
Mice, Inbred NOD
Mice, SCID
Neovascularization, Pathologic--diet therapy
Vascular Endothelial Growth Factor A--biosynthesis
Vascular Endothelial Growth Factor Receptor-2--biosynthesis
Xenograft Model Antitumor Assays