TRIP13 promotes error-prone nonhomologous end joining and induces chemoresistance in head and neck cancer. [electronic resource]
- Nature communications Jul 2014
- 4527 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural
2041-1723
10.1038/ncomms5527 doi
ATPases Associated with Diverse Cellular Activities Animals Antineoplastic Agents--pharmacology Carcinoma, Squamous Cell--drug therapy Carrier Proteins--antagonists & inhibitors Cell Cycle Proteins Cell Line, Transformed Cell Line, Tumor Cell Movement Cell Transformation, Neoplastic--genetics Chick Embryo Chorioallantoic Membrane--blood supply DNA Breaks, Double-Stranded DNA End-Joining Repair DNA-Activated Protein Kinase--antagonists & inhibitors Drug Resistance, Neoplasm--genetics Gene Expression Regulation, Neoplastic Head and Neck Neoplasms--drug therapy Humans Injections, Subcutaneous Keratinocytes--drug effects Mice Mice, Nude NIH 3T3 Cells Nuclear Proteins--antagonists & inhibitors RNA, Small Interfering--genetics Signal Transduction Squamous Cell Carcinoma of Head and Neck Xenograft Model Antitumor Assays