Yamazaki, Shinji <br/><br/>
Translational pharmacokinetic-pharmacodynamic modeling for an orally available novel inhibitor of anaplastic lymphoma kinase and c-Ros oncogene 1.  [electronic resource] 

 -  The Journal of pharmacology and experimental therapeutics  Oct 2014 
 - 67-76 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1521-0103 
<br/><br/><label>Standard No.: </label>10.1124/jpet.114.217141  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Administration, Oral<br/>Aminopyridines<br/>Anaplastic Lymphoma Kinase<br/>Animals<br/>Antineoplastic Agents--administration & dosage<br/>Cell Line, Tumor<br/>Female<br/>Humans<br/>Lactams<br/>Lactams, Macrocyclic--pharmacokinetics<br/>Mice<br/>Models, Biological<br/>NIH 3T3 Cells<br/>Protein Kinase Inhibitors--administration & dosage<br/>Protein-Tyrosine Kinases--antagonists & inhibitors<br/>Proto-Oncogene Proteins--antagonists & inhibitors<br/>Pyrazoles<br/>Receptor Protein-Tyrosine Kinases--antagonists & inhibitors