Chiu, M

Glutamine depletion by crisantaspase hinders the growth of human hepatocellular carcinoma xenografts. [electronic resource] - British journal of cancer Sep 2014 - 1159-67 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1532-1827

10.1038/bjc.2014.425 doi


Animals
Antineoplastic Agents--therapeutic use
Asparaginase--pharmacology
Asparagine--blood
Cadherins--analysis
Carcinoma, Hepatocellular--drug therapy
Enzyme Inhibitors--therapeutic use
Glutamate-Ammonia Ligase--antagonists & inhibitors
Glutamine--analysis
Hep G2 Cells
Humans
Ki-67 Antigen--analysis
Liver Neoplasms--drug therapy
Male
Methionine Sulfoximine--therapeutic use
Mice
Mice, Nude
Mutation
Tumor Burden--drug effects
Xenograft Model Antitumor Assays
beta Catenin--analysis