Disruption of Runx1 and Runx3 leads to bone marrow failure and leukemia predisposition due to transcriptional and DNA repair defects. [electronic resource]
- Cell reports Aug 2014
- 767-82 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
2211-1247
10.1016/j.celrep.2014.06.046 doi
Animals Bone Marrow--metabolism Core Binding Factor Alpha 2 Subunit--genetics Core Binding Factor Alpha 3 Subunit--genetics DNA Repair Fanconi Anemia--genetics Fanconi Anemia Complementation Group D2 Protein--metabolism Gene Deletion Genetic Predisposition to Disease HCT116 Cells HEK293 Cells HeLa Cells Humans Leukemia--genetics Mice Mice, Inbred C57BL