TY - GEN AU - Hasbi,Ahmed AU - Perreault,Melissa L AU - Shen,Maurice Y F AU - Zhang,Lucia AU - To,Ryan AU - Fan,Theresa AU - Nguyen,Tuan AU - Ji,Xiaodong AU - O'Dowd,Brian F AU - George,Susan R TI - A peptide targeting an interaction interface disrupts the dopamine D1-D2 receptor heteromer to block signaling and function in vitro and in vivo: effective selective antagonism SN - 1530-6860 PY - 2015///0127 KW - Animals KW - Brain KW - metabolism KW - Calcium Signaling KW - physiology KW - Dopamine KW - Dopamine D2 Receptor Antagonists KW - pharmacology KW - Male KW - Neurons KW - drug effects KW - Peptides KW - Protein Multimerization KW - Rats, Sprague-Dawley KW - Receptors, Dopamine D1 KW - antagonists & inhibitors KW - Receptors, Dopamine D2 N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural UR - https://doi.org/10.1096/fj.14-254037 ER -