Sahin, Ilyas

Targeting survival and cell trafficking in multiple myeloma and Waldenstrom macroglobulinemia using pan-class I PI3K inhibitor, buparlisib. [electronic resource] - American journal of hematology Nov 2014 - 1030-6 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1096-8652

10.1002/ajh.23814 doi


Aminopyridines--pharmacology
Animals
Antineoplastic Agents--pharmacology
Apoptosis--drug effects
Cell Adhesion--drug effects
Cell Cycle--drug effects
Cell Line
Cell Line, Tumor
Chemotaxis--drug effects
Coculture Techniques
Drug Screening Assays, Antitumor
Female
Fibronectins
Humans
Mesenchymal Stem Cells--cytology
Mice
Mice, SCID
Morpholines--pharmacology
Multiple Myeloma--enzymology
Neoplasm Invasiveness
Neoplasm Proteins--antagonists & inhibitors
Phosphoinositide-3 Kinase Inhibitors
Protein Kinase Inhibitors--pharmacology
RNA Interference
RNA, Small Interfering--pharmacology
Receptors, CXCR4--biosynthesis
Waldenstrom Macroglobulinemia--enzymology
Xenograft Model Antitumor Assays