Dail, Monique <br/><br/>
Loss of oncogenic Notch1 with resistance to a PI3K inhibitor in T-cell leukaemia.  [electronic resource] 

 -  Nature  Sep 2014 
 - 512-6 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1476-4687 
<br/><br/><label>Standard No.: </label>10.1038/nature13495  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Benzamides--pharmacology<br/>Clone Cells--drug effects<br/>Diphenylamine--analogs & derivatives<br/>Down-Regulation--drug effects<br/>Drug Resistance, Neoplasm--drug effects<br/>Drug Synergism<br/>Genes, ras--genetics<br/>Indazoles--pharmacology<br/>Male<br/>Mice<br/>Mice, Inbred C57BL<br/>Mitogen-Activated Protein Kinase Kinases--antagonists & inhibitors<br/>Phosphoinositide-3 Kinase Inhibitors<br/>Precursor T-Cell Lymphoblastic Leukemia-Lymphoma--drug therapy<br/>Protein Kinase Inhibitors--pharmacology<br/>Protein Structure, Tertiary<br/>Proto-Oncogene Proteins c-akt--metabolism<br/>Receptor, Notch1--chemistry<br/>Signal Transduction--drug effects<br/>Sulfonamides--pharmacology