Substitution of a single amino acid (aspartic acid for histidine) converts the functional activity of human complement C4B to C4A. [electronic resource]
- Proceedings of the National Academy of Sciences of the United States of America Sep 1990
- 6868-72 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
0027-8424
10.1073/pnas.87.17.6868 doi
Animals Aspartic Acid Base Sequence Cell Line Complement C4a--biosynthesis Complement C4b--biosynthesis Genetic Vectors Hemolysis Histidine Humans Kinetics Molecular Sequence Data Mutation Oligonucleotide Probes Plasmids Recombinant Proteins--biosynthesis Transfection