Takhi, Mohamed <br/><br/>
Discovery of azetidine based ene-amides as potent bacterial enoyl ACP reductase (FabI) inhibitors.  [electronic resource] 

 -  European journal of medicinal chemistry  Sep 2014 
 - 382-94 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1768-3254 
<br/><br/><label>Standard No.: </label>10.1016/j.ejmech.2014.07.036  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Amides--chemistry<br/>Animals<br/>Azetidines--chemistry<br/>Crystallography, X-Ray<br/>Dose-Response Relationship, Drug<br/>Drug Discovery<br/>Enoyl-(Acyl-Carrier-Protein) Reductase (NADH)--metabolism<br/>Enzyme Inhibitors--chemistry<br/>Male<br/>Mice<br/>Microsomes, Liver--metabolism<br/>Models, Molecular<br/>Molecular Structure<br/>Staphylococcus aureus--cytology<br/>Structure-Activity Relationship