Pang, Xiaoming

Homocysteine induces the expression of C-reactive protein via NMDAr-ROS-MAPK-NF-κB signal pathway in rat vascular smooth muscle cells. [electronic resource] - Atherosclerosis Sep 2014 - 73-81 p. digital

Publication Type: Journal Article

1879-1484

10.1016/j.atherosclerosis.2014.06.021 doi


Animals
Atherosclerosis--etiology
C-Reactive Protein--biosynthesis
Cells, Cultured
Dizocilpine Maleate--pharmacology
Gene Expression Regulation--drug effects
Homocysteine--pharmacology
Hyperhomocysteinemia--complications
Interleukins--antagonists & inhibitors
MAP Kinase Signaling System--drug effects
Male
Methionine--toxicity
Mitogen-Activated Protein Kinases--metabolism
Myocytes, Smooth Muscle--drug effects
NF-kappa B--metabolism
Onium Compounds--pharmacology
Phosphorylation--drug effects
Protein Kinase Inhibitors--pharmacology
Protein Processing, Post-Translational--drug effects
RNA, Messenger--biosynthesis
Rats
Rats, Sprague-Dawley
Reactive Oxygen Species--metabolism
Receptors, N-Methyl-D-Aspartate--biosynthesis
Signal Transduction--drug effects
Superoxides--metabolism
Thenoyltrifluoroacetone--pharmacology