Potentiation of tumor responses to DNA damaging therapy by the selective ATR inhibitor VX-970. [electronic resource]
- Oncotarget Jul 2014
- 5674-85 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural
1949-2553
10.18632/oncotarget.2158 doi
Animals Antineoplastic Combined Chemotherapy Protocols--pharmacology Ataxia Telangiectasia Mutated Proteins--antagonists & inhibitors Cell Line, Tumor Cisplatin--administration & dosage DNA--drug effects DNA Damage Drug Synergism Female Humans Isoxazoles--pharmacology Mice Mice, SCID Phosphorylation Protein Kinase Inhibitors--administration & dosage Pyrazines--pharmacology Random Allocation Signal Transduction Xenograft Model Antitumor Assays