Gurbel, P A

The effect of CYP2C19 gene polymorphisms on the pharmacokinetics and pharmacodynamics of prasugrel 5-mg, prasugrel 10-mg and clopidogrel 75-mg in patients with coronary artery disease. [electronic resource] - Thrombosis and haemostasis Sep 2014 - 589-97 p. digital

Publication Type: Clinical Trial, Phase I; Comparative Study; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

2567-689X

10.1160/TH13-10-0891 doi


Aged
Clinical Protocols
Clopidogrel
Coronary Artery Disease--drug therapy
Cytochrome P-450 CYP2C19--genetics
Female
Genotype
Humans
Male
Middle Aged
Phenotype
Piperazines--administration & dosage
Platelet Aggregation--drug effects
Platelet Aggregation Inhibitors--administration & dosage
Polymorphism, Genetic
Prasugrel Hydrochloride
Thiophenes--administration & dosage
Ticlopidine--administration & dosage
Treatment Outcome