de la Croix Ndong, Jean <br/><br/>
Asfotase-α improves bone growth, mineralization and strength in mouse models of neurofibromatosis type-1.  [electronic resource] 

 -  Nature medicine  Aug 2014 
 - 904-10 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S. 
<br/><br/><label>ISSN: </label>1546-170X 
<br/><br/><label>Standard No.: </label>10.1038/nm.3583  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Adolescent<br/>Alkaline Phosphatase--biosynthesis<br/>Animals<br/>Bone Development--drug effects<br/>Bone Diseases, Developmental--genetics<br/>Bone Morphogenetic Protein 2--genetics<br/>Calcification, Physiologic--drug effects<br/>Cells, Cultured<br/>Child<br/>Child, Preschool<br/>Collagen Type I--biosynthesis<br/>Collagen Type I, alpha 1 Chain<br/>Collagen Type II--genetics<br/>Diphosphates--metabolism<br/>Disease Models, Animal<br/>Durapatite--metabolism<br/>Humans<br/>Immunoglobulin G--therapeutic use<br/>Infant<br/>Mice<br/>Mice, Inbred C57BL<br/>Mice, Knockout<br/>Mitogen-Activated Protein Kinases--metabolism<br/>Neurofibromatosis 1--drug therapy<br/>Neurofibromin 1--genetics<br/>Osteoblasts--enzymology<br/>Osteogenesis--genetics<br/>Phosphate Transport Proteins--biosynthesis<br/>Phosphoric Diester Hydrolases--biosynthesis<br/>Pyrophosphatases--biosynthesis<br/>Recombinant Fusion Proteins--therapeutic use<br/>Sp7 Transcription Factor<br/>Transcription Factors--genetics