TY - GEN AU - Zheng,Xingnan AU - Zhai,Bo AU - Koivunen,Peppi AU - Shin,Sandra J AU - Lu,Gang AU - Liu,Jiayun AU - Geisen,Christoph AU - Chakraborty,Abhishek A AU - Moslehi,Javid J AU - Smalley,David M AU - Wei,Xin AU - Chen,Xian AU - Chen,Zhengming AU - Beres,Justine M AU - Zhang,Jing AU - Tsao,Jen Lan AU - Brenner,Mitchell C AU - Zhang,Yuqing AU - Fan,Cheng AU - DePinho,Ronald A AU - Paik,Jihye AU - Gygi,Steven P AU - Kaelin,William G AU - Zhang,Qing TI - Prolyl hydroxylation by EglN2 destabilizes FOXO3a by blocking its interaction with the USP9x deubiquitinase SN - 1549-5477 PY - 2014///0902 KW - Animals KW - Cell Line KW - Cells, Cultured KW - Cyclin D1 KW - genetics KW - Forkhead Box Protein O3 KW - Forkhead Transcription Factors KW - metabolism KW - Gene Expression Regulation, Neoplastic KW - Hydroxylation KW - Hypoxia-Inducible Factor-Proline Dioxygenases KW - MCF-7 Cells KW - Mice KW - Protein Binding KW - Protein Stability KW - Ubiquitin Thiolesterase N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1101/gad.242131.114 ER -