TY  - GEN
AU  - Abuo-Rahma,Gamal El-Din A A
AU  - Abdel-Aziz,Mohamed
AU  - Farag,Nahla A
AU  - Kaoud,Tamer S
TI  - Novel 1-[4-(Aminosulfonyl)phenyl]-1H-1,2,4-triazole derivatives with remarkable selective COX-2 inhibition: design, synthesis, molecular docking, anti-inflammatory and ulcerogenicity studies
SN  - 1768-3254
PY  - 2015///0402
KW  - Animals
KW  - Anti-Inflammatory Agents, Non-Steroidal
KW  - adverse effects
KW  - Chemistry Techniques, Synthetic
KW  - Cyclooxygenase 2
KW  - chemistry
KW  - Cyclooxygenase 2 Inhibitors
KW  - Drug Design
KW  - Humans
KW  - Male
KW  - Molecular Docking Simulation
KW  - Protein Conformation
KW  - Quantitative Structure-Activity Relationship
KW  - Rats
KW  - Stomach Ulcer
KW  - chemically induced
KW  - Substrate Specificity
KW  - Triazoles
KW  - chemical synthesis
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1016/j.ejmech.2014.06.049
ER  -