TY  - GEN
AU  - Wakimoto,Toshiyuki
AU  - Egami,Yoko
AU  - Nakashima,Yu
AU  - Wakimoto,Yukihiko
AU  - Mori,Takahiro
AU  - Awakawa,Takayoshi
AU  - Ito,Takuya
AU  - Kenmoku,Hiromichi
AU  - Asakawa,Yoshinori
AU  - Piel,Jörn
AU  - Abe,Ikuro
TI  - Calyculin biogenesis from a pyrophosphate protoxin produced by a sponge symbiont
SN  - 1552-4469
PY  - 2014///1006
KW  - Animals
KW  - Antineoplastic Agents
KW  - pharmacology
KW  - Diphosphates
KW  - metabolism
KW  - Drug Screening Assays, Antitumor
KW  - HeLa Cells
KW  - Humans
KW  - Leukemia
KW  - drug therapy
KW  - Marine Toxins
KW  - Metagenome
KW  - Mice
KW  - Molecular Sequence Data
KW  - Multigene Family
KW  - Organophosphates
KW  - chemistry
KW  - Oxazoles
KW  - Phosphorylation
KW  - Phosphotransferases
KW  - genetics
KW  - Phylogeny
KW  - Polyketide Synthases
KW  - Porifera
KW  - microbiology
KW  - RNA, Ribosomal, 16S
KW  - Symbiosis
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1038/nchembio.1573
ER  -