TY - GEN AU - Zaafar,Dalia K AU - Zaitone,Sawsan A AU - Moustafa,Yasser M TI - Role of metformin in suppressing 1,2-dimethylhydrazine-induced colon cancer in diabetic and non-diabetic mice: effect on tumor angiogenesis and cell proliferation SN - 1932-6203 PY - 2015///1002 KW - 1,2-Dimethylhydrazine KW - toxicity KW - Animals KW - Antigens, CD34 KW - metabolism KW - Antineoplastic Agents KW - therapeutic use KW - Cell Proliferation KW - drug effects KW - Colon KW - Colonic Neoplasms KW - chemically induced KW - Diabetes Mellitus, Experimental KW - drug therapy KW - Diet, High-Fat KW - Drug Therapy, Combination KW - Hypoglycemic Agents KW - pharmacology KW - Insulin-Like Growth Factor I KW - analysis KW - Male KW - Metformin KW - Mice KW - Neovascularization, Pathologic KW - Organoplatinum Compounds KW - Oxaliplatin KW - Receptor, IGF Type 1 KW - Survival Rate KW - Vascular Endothelial Growth Factor A KW - blood N1 - Publication Type: Journal Article UR - https://doi.org/10.1371/journal.pone.0100562 ER -