TY - GEN AU - Xu,Lihong AU - Stevens,Janine AU - Hilton,Mary Beth AU - Seaman,Steven AU - Conrads,Thomas P AU - Veenstra,Timothy D AU - Logsdon,Daniel AU - Morris,Holly AU - Swing,Deborah A AU - Patel,Nimit L AU - Kalen,Joseph AU - Haines,Diana C AU - Zudaire,Enrique AU - St Croix,Brad TI - COX-2 inhibition potentiates antiangiogenic cancer therapy and prevents metastasis in preclinical models SN - 1946-6242 PY - 2015///0219 KW - Angiogenesis Inhibitors KW - pharmacology KW - Animals KW - Axitinib KW - Carcinogenesis KW - pathology KW - Cell Line, Tumor KW - Clone Cells KW - Cyclooxygenase 2 KW - metabolism KW - Cyclooxygenase 2 Inhibitors KW - Dinoprostone KW - Female KW - Humans KW - Imidazoles KW - Indazoles KW - Liver Neoplasms KW - blood supply KW - Mammary Neoplasms, Experimental KW - Mice KW - Neoadjuvant Therapy KW - Signal Transduction KW - drug effects KW - Survival Analysis KW - Vascular Endothelial Growth Factor A KW - Xenograft Model Antitumor Assays N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural UR - https://doi.org/10.1126/scitranslmed.3008455 ER -