TY  - GEN
AU  - Turlington,Mark
AU  - Noetzel,Meredith J
AU  - Bridges,Thomas M
AU  - Vinson,Paige N
AU  - Steckler,Thomas
AU  - Lavreysen,Hilde
AU  - Mackie,Claire
AU  - Bartolomé-Nebreda,José M
AU  - Conde-Ceide,Susana
AU  - Tong,Han Min
AU  - Macdonald,Gregor J
AU  - Daniels,J Scott
AU  - Jones,Carrie K
AU  - Niswender,Colleen M
AU  - Conn,P Jeffrey
AU  - Lindsley,Craig W
AU  - Stauffer,Shaun R
TI  - Discovery and SAR of a novel series of metabotropic glutamate receptor 5 positive allosteric modulators with high ligand efficiency
SN  - 1464-3405
PY  - 2015///0305
KW  - Allosteric Regulation
KW  - drug effects
KW  - Animals
KW  - Cell Line
KW  - Dose-Response Relationship, Drug
KW  - Drug Discovery
KW  - Humans
KW  - Ligands
KW  - Molecular Structure
KW  - Piperidones
KW  - chemical synthesis
KW  - Pyrazoles
KW  - Rats
KW  - Receptor, Metabotropic Glutamate 5
KW  - metabolism
KW  - Structure-Activity Relationship
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1016/j.bmcl.2014.04.087
ER  -