Turlington, Mark <br/><br/>
Discovery and SAR of a novel series of metabotropic glutamate receptor 5 positive allosteric modulators with high ligand efficiency.  [electronic resource] 

 -  Bioorganic & medicinal chemistry letters  Aug 2014 
 - 3641-6 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1464-3405 
<br/><br/><label>Standard No.: </label>10.1016/j.bmcl.2014.04.087  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Allosteric Regulation--drug effects<br/>Animals<br/>Cell Line<br/>Dose-Response Relationship, Drug<br/>Drug Discovery<br/>Humans<br/>Ligands<br/>Molecular Structure<br/>Piperidones--chemical synthesis<br/>Pyrazoles--chemical synthesis<br/>Rats<br/>Receptor, Metabotropic Glutamate 5--metabolism<br/>Structure-Activity Relationship