TY - GEN AU - Wang,Ying-Ming AU - Tsai,Inn-Ho AU - Chen,Jin-Mei AU - Cheng,An-Chun AU - Khoo,Kay-Hooi TI - Correlation between the glycan variations and defibrinogenating activities of acutobin and its recombinant glycoforms SN - 1932-6203 PY - 2015///0312 KW - Animals KW - Biocatalysis KW - drug effects KW - CHO Cells KW - Cricetinae KW - Cricetulus KW - Crotalid Venoms KW - chemistry KW - Enzyme Stability KW - Fibrin Fibrinogen Degradation Products KW - metabolism KW - Fibrinolysis KW - Fibrinolytic Agents KW - pharmacology KW - Glycosylation KW - HEK293 Cells KW - Humans KW - Hydrolysis KW - Kinetics KW - Mice KW - Molecular Weight KW - Peptide Mapping KW - Peptide-N4-(N-acetyl-beta-glucosaminyl) Asparagine Amidase KW - Peptides KW - Polysaccharides KW - Protein Isoforms KW - Rabbits KW - Recombinant Proteins KW - Serum Globulins KW - Substrate Specificity KW - Thrombin N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1371/journal.pone.0100354 ER -