TY - GEN AU - Smith,Claire M AU - Sandrini,Sara AU - Datta,Sumit AU - Freestone,Primrose AU - Shafeeq,Sulman AU - Radhakrishnan,Priya AU - Williams,Gwyneth AU - Glenn,Sarah M AU - Kuipers,Oscar P AU - Hirst,Robert A AU - Easton,Andrew J AU - Andrew,Peter W AU - O'Callaghan,Christopher TI - Respiratory syncytial virus increases the virulence of Streptococcus pneumoniae by binding to penicillin binding protein 1a. A new paradigm in respiratory infection SN - 1535-4970 PY - 2014///0908 KW - Animals KW - Bacterial Adhesion KW - Biomarkers KW - metabolism KW - Blotting, Western KW - Cells, Cultured KW - Coinfection KW - Epithelial Cells KW - Female KW - Gene Expression Regulation, Bacterial KW - Humans KW - Mice KW - Microscopy, Confocal KW - Penicillin-Binding Proteins KW - Pneumonia, Pneumococcal KW - Real-Time Polymerase Chain Reaction KW - Respiratory Mucosa KW - Respiratory Syncytial Virus Infections KW - Respiratory Syncytial Viruses KW - Streptococcus pneumoniae KW - genetics KW - Transcriptome KW - Up-Regulation KW - Viral Fusion Proteins KW - Virulence N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1164/rccm.201311-2110OC ER -