Zhang, Song <br/><br/>
A novel suberoylanilide hydroxamic acid histone deacetylase inhibitor derivative, N25, exhibiting improved antitumor activity in both human U251 and H460 cells.  [electronic resource] 

 -  Asian Pacific journal of cancer prevention : APJCP  2014 
 - 4331-8 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>2476-762X 
<br/><br/><label>Standard No.: </label>10.7314/apjcp.2014.15.10.4331  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Acetylation<br/>Anilides--pharmacokinetics<br/>Antineoplastic Agents--pharmacology<br/>Apoptosis--drug effects<br/>Brain Neoplasms--drug therapy<br/>Cell Division--drug effects<br/>Cell Line, Tumor<br/>Cell Proliferation--drug effects<br/>Cyclin-Dependent Kinase Inhibitor p21--biosynthesis<br/>Drug Screening Assays, Antitumor<br/>G1 Phase Cell Cycle Checkpoints--drug effects<br/>Glioma--drug therapy<br/>Histone Deacetylase Inhibitors--pharmacology<br/>Histone Deacetylases<br/>Histones--metabolism<br/>Humans<br/>Hydroxamic Acids--pharmacokinetics<br/>Lung Neoplasms--drug therapy<br/>M Phase Cell Cycle Checkpoints--drug effects<br/>Molecular Docking Simulation<br/>Repressor Proteins--antagonists & inhibitors<br/>Tumor Suppressor Protein p53--biosynthesis<br/>Vorinostat