Abdelsamie, Ahmed S

Inhibition of 17β-HSD1: SAR of bicyclic substituted hydroxyphenylmethanones and discovery of new potent inhibitors with thioether linker. [electronic resource] - European journal of medicinal chemistry Jul 2014 - 394-406 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1768-3254

10.1016/j.ejmech.2014.05.074 doi


17-Hydroxysteroid Dehydrogenases--antagonists & inhibitors
Animals
Dose-Response Relationship, Drug
Drug Discovery
Enzyme Inhibitors--chemical synthesis
Humans
Mice
Models, Molecular
Molecular Structure
Phenols--chemical synthesis
Structure-Activity Relationship
Sulfides--chemistry