TY - GEN AU - Zhu,Jianqiong AU - Chin,Kyung AU - Aerbajinai,Wulin AU - Kumkhaek,Chutima AU - Li,Hongzhen AU - Rodgers,Griffin P TI - Hydroxyurea-inducible SAR1 gene acts through the Giα/JNK/Jun pathway to regulate γ-globin expression SN - 1528-0020 PY - 2015///0427 KW - Antineoplastic Agents KW - pharmacology KW - Apoptosis KW - drug effects KW - Binding Sites KW - genetics KW - Blotting, Western KW - Cell Cycle Checkpoints KW - Cells, Cultured KW - Fetal Hemoglobin KW - GTP-Binding Protein alpha Subunits, Gi-Go KW - metabolism KW - Gene Expression KW - Humans KW - Hydroxyurea KW - JNK Mitogen-Activated Protein Kinases KW - K562 Cells KW - Monomeric GTP-Binding Proteins KW - NF-kappa B KW - Promoter Regions, Genetic KW - Proto-Oncogene Proteins c-jun KW - RNA Interference KW - Reverse Transcriptase Polymerase Chain Reaction KW - Signal Transduction KW - ets-Domain Protein Elk-1 KW - gamma-Globins N1 - Publication Type: Journal Article; Research Support, N.I.H., Intramural UR - https://doi.org/10.1182/blood-2013-10-534842 ER -