TY - GEN AU - Manns,Michael AU - Marcellin,Patrick AU - Poordad,Fred AU - de Araujo,Evaldo Stanislau Affonso AU - Buti,Maria AU - Horsmans,Yves AU - Janczewska,Ewa AU - Villamil,Federico AU - Scott,Jane AU - Peeters,Monika AU - Lenz,Oliver AU - Ouwerkerk-Mahadevan,Sivi AU - De La Rosa,Guy AU - Kalmeijer,Ronald AU - Sinha,Rekha AU - Beumont-Mauviel,Maria TI - Simeprevir with pegylated interferon alfa 2a or 2b plus ribavirin in treatment-naive patients with chronic hepatitis C virus genotype 1 infection (QUEST-2): a randomised, double-blind, placebo-controlled phase 3 trial SN - 1474-547X PY - 2014///0818 KW - Adolescent KW - Adult KW - Aged KW - Antiviral Agents KW - administration & dosage KW - Double-Blind Method KW - Drug Administration Schedule KW - Drug Therapy, Combination KW - Female KW - Genotype KW - Hepacivirus KW - genetics KW - Hepatitis C, Chronic KW - drug therapy KW - Heterocyclic Compounds, 3-Ring KW - Humans KW - Interferon alpha-2 KW - Interferon-alpha KW - Male KW - Middle Aged KW - Polyethylene Glycols KW - Recombinant Proteins KW - Ribavirin KW - Simeprevir KW - Sulfonamides KW - Treatment Outcome N1 - Publication Type: Clinical Trial, Phase III; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1016/S0140-6736(14)60538-9 ER -